This mode is used to perform univariate feature selection with fold change. We compare each feature individually for evidence of differential expression in the two prediction classes. If the fold change is more than a threshold , then the feature is selected as an informative biomarker.
It is implemented by org.bdval.DiscoverWithFoldChange.java.
Mode Parameters
The following options are available in this mode
| Flag | Arguments | Required | Description |
|---|---|---|---|
--ratio | ratio | no | The fold change ratio used as threshold. Default is 2 fold changes. |
--output-gene-list | n/a | no | Write features to the output in the tissueinfo gene list format. |
--report-max-probes | report-max-probes | no | Restrict output to the top ranked probes. This option works in conjunction with the ratio and can further restrict the output. |
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